Ghouls and Super Mutants. They're icons of the Fallout series. Previously, there were major communities and factions composed of them. The Master's Army, Necropolis, Broken Hills, Gecko, etc. Powerful or influential communities of these human off-shoots. However, in Fallout: New Vegas, their impact on the gameworld is negligible in comparison. Isolationist communities like Jacobstown or Black Mountain, or the REPCONN ghouls, don't influence the gameworld nearly as much- they never effect anymore people than small communities like Novac. This trend only makes sense: the further you get from the Great War, and the further you get from the destruction of the Vats, less and less mutants will be present. And while new ghouls are seen (rarely), new Super Mutants are not- so if this continues, will we entirely cease to see mutants? Even NCR obviously has a largely human population. So will the next Fallout game in the west be devoid of it's icons? Are mutants slowly slipping into the background, for human factions like Caesar's Legion and the NCR to take the show? I think that's perfectly dull.