Just like in previous games, this game has a lot of opportunities to gain karma. Maybe too much. You gain karma from killing enemies such as Fiends, Escaped Convicts, and Feral Ghouls. Because of this, regardless of how you solve certain quests and gain evil karma or remain neutral, it's next to impossible to finish the game with neutral or evil karma, unless you go on a killing or stealing spree. I suppose this is true for the previous games. Where the only way to have a lot of evil karma is by killing everyone you meet. Of course, there are times where you'll be forced to kill creatures and people that will give you good karma. This would make getting Ain't Like That Now or Just Lucky I'm Alive difficult. Fallout 3 would probably be the easiest game to be evil as there are several quests that can reduce your karma down to the lowest level. Is is just me, or do the producers of this series want you to be the good guy despite having opportunities for evil?