It could had been more of a western, rather, it could had applied those tropes more, that's for sure.
We have mines but they're all dungeons. A sulfur mine or two, maybe a old gold mine. A quest line about a boom might had been nice rather than that odd Powder Ganger spinoff who is apparently important enough to get an ending slide despite not fighting at the battle?
More town-related stuff like dealing with corrupt sheriffs and lawmen and mayors. We have one ornery deputy, a shitty motel owner, and that's about it. West and North Vegas are bastions of anarchy, apparently, with little to no problems up top.
Caravan hits, various runs, even more courier work would had all been welcome and fleshed out the game a bit and added a nice layer of 'western', along with little details in avatar customization via clothes and armor.